nocturnal leg cramps: vitamin K2 helps
A recent study found that vitamin K2 decreased nocturnal leg cramps in older patients (see nocturnal cramps vit K2 helps JAMAintmed2024 in dropbox, or doi:10.1001/jamainternmed.2024.5726) Details: --199 community-dwelling individuals 65 years and older participated in this multicenter, double-blind, placebo-controlled randomized clinical trial conducted in China between September 2022 and December 2023 -- all had 2 or more documented episodes of nocturnal leg cramps (NLCs) during 2 weeks of screening -- 103 participants were randomly assigned to 180 μg vitamin K2 (menaquinone 7) capsules or a similar-looking placebo every day for 8 weeks, 96 patients were randomized to placebo -- 108 (54%) were female, mean age 72 years -- hypertension 68%, diabetes 51%, serum creatinine 0.89 mg/dL -- baseline weekly frequency of cramps was 2.60 in the vitamin K2 group and 2.71 in the placebo group -- patients with other relevant conditions (r...