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racial disparities, stress and mortality

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  a recent study found (again) that racial disparities are associated with stress, chronic inflammation and increased mortality (see  racial disparities stress and mortality JAMA2026  in dropbox, or doi:10.1001/jamanetworkopen.2025.54701) Details : -- The St Louis Personality and Aging Network recruited 1554 participants who lived in the metropolitan area of St Louis, Missouri. Participants were required to have a mailing address to permit longitudinal follow-up and sixth grade reading to facilitate understanding the consent form.  this was a longitudinal cohort study from 2007 to 2011; d ata were analyzed from April to September 2025. -- A lifespan cumulative stress factor was used to assess childhood maltreatment, lifetime trauma exposure, research assistant-verified stressful life events, major experiences of discrimination, and indices of socioeconomic status -- 505 Black participants (32.5% of the group) and 1049 White participants  (67.5%)  were ...
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AI detecting early pancreatic cancer from CT scan

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  a recent study found that using artificial intelligence (AI) was more accurate in detecting early pancreatic cancer from a CT scan than trained radiologists   ( pancreatic cancer AI radiology LancetOnc2026  in dropbox, or https://doi.org/10.1016/S1470-2045(25)00567-4) Details : --this international, paired, non-inferiority, confirmatory, observational study (PANORAMA) compared AI diagnoses of pancreatic ductal adenocarcinoma (PDAC) between trained radiologists and an AI system developed to read/interpret contrast-enhanced CT scans     -- the AI system was trained and externally validated within an international benchmark, with a cohort of these 2310 patients from four tertiary care centers in the Netherlands and the USA for training (n=2224) and tuning (n=86), and a sequestered cohort of 1130 patients from five tertiary care centers (the Netherlands, Sweden, and Norway) for testing. -- AI system used: the top three performing algorithms were deep learning...
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