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AI detecting early pancreatic cancer from CT scan

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  a recent study found that using artificial intelligence (AI) was more accurate in detecting early pancreatic cancer from a CT scan than trained radiologists   ( pancreatic cancer AI radiology LancetOnc2026  in dropbox, or https://doi.org/10.1016/S1470-2045(25)00567-4) Details : --this international, paired, non-inferiority, confirmatory, observational study (PANORAMA) compared AI diagnoses of pancreatic ductal adenocarcinoma (PDAC) between trained radiologists and an AI system developed to read/interpret contrast-enhanced CT scans     -- the AI system was trained and externally validated within an international benchmark, with a cohort of these 2310 patients from four tertiary care centers in the Netherlands and the USA for training (n=2224) and tuning (n=86), and a sequestered cohort of 1130 patients from five tertiary care centers (the Netherlands, Sweden, and Norway) for testing. -- AI system used: the top three performing algorithms were deep learning...

gout: uric acid target less than 6 prevented cardiovascular problems

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gout: uric acid target <6 prevented cardiovascular problems  Modest, Geoffrey (HMFP - Medicine) ​ Modest, Geoffrey (HMFP - Medicine) ​ a new study found that in patients with gout, a serum urate target level <6 prevented cardiovascular problems (see  gout dec UA to less than 6 dec cardiovasc JAMAintmed2026  or doi:10.1001/jamainternmed.2025.7453) Details : -- 109,504 patients  who had gout and were new users of urate lowering medications were identified in the primary care database from the UK's Clinical Practice Research Datalink Aurum linking hospitalization and mortality records , from January 1, 2007, to March 29, 2021 and followed up to 5 years -- all were at 18yo or older, had a pretreatment serum urate (SU) level higher than 6mg/dL, and were newly prescribed urate-lowering therapy (ULT), with data a nalyzed from May 2024 to January 2025 -- all had  a first coding for gout, gout tophi, or a gout flare in their records -- patients were assigned ...