Aspirin in elderly increases anemia
A secondary analysis of the ASPREE study found an increase in anemia in the elderly taking low-dose aspirin (see aspirin inc anemia AnnIntMed2023 in dropbox or doi:10.7326/M23-0675 ). Details : -- 18,153 persons were randomly assigned to 100 mg of aspirin daily or placebo in the ASPirin in Reducing Events in the Elderly (ASPREE) trial of community-dwelling persons at least 70 years old, or Black or Hispanic persons at least 65 years old, in Australia and the US, with enrollment from 2010 to 2015 -- mean age 74, 56% female, 87% were white from Australia, 6% were white from the US, 3.9% Black , 2.5% Hispanic -- all were community-based: 32% lived at home alone, 68% with others -- smoking status was never in 55%/former in 41%/current in 4%; cancer history 19%; BMI 24% normal/29% obese/45% overweight; waist circumference high in 45% -- mean baseline hemoglobin 14.2 g/dL -- mean blood pressure 139/77, eGFR 74, CKD 29%, hypertension 74%, ...