COVID: thrombi, inflammation, bradykinin, vitamin D...
sorry, this blog is a bit long, but i wanted to bring in several different studies since it seems there is a large constellation of events triggered by the SARS-CoV-2 virus, and it seems important to look at a bigger picture than what is presented in individual studies with individual treatments. ------------------------- a small study documented diffuse immunothrombotic dysregulation and coagulopathy associated with Covid-19 pneumonia (see covid microthrombi immunodysregulation circ2020 in dropbox, or doi.org/10.1161/CIRCULATIONAHA.120.048488 ) Details : --38 patients with PCR-documented Covid-19, and 24 non-Covid controls --Covid group: 18 severe cases, requiring intubation and ICU treatment; 20 had intermediate severity, requiring at most non-invasive supplemental oxygen --one patient died, age 91, declining intensive care treatment, and had an autopsy; 4 additional patients had lung specimens, and 5 died from c...