Gabapentinoids association with severe COPD exacerbations
A population-based observational study found that gabapentinoids (gabapentin and pregabalin) were associated with severe COPD exacerbations (see gabapentin assoc severe COPD AnnIntMed2024 in dropbox, or doi:10.7326/M23-0849) Details: -- a large data-mining study from Québec access ed three computerized healthcare databases, collecting information on demographics, medical services, and dispensed outpatient prescriptions. this included information on medical services for all Québec residents (though one of the databases only included those who did not have private medication insurance, 43% of the population ). These researchers also accessed information on all hospitalizations, procedures, and vital statistics including date, cause, and place of death -- there were some differences in the demographics and comorbidities of those individuals on gabapentinoids , based on whether they were used for epilepsy, neuropathic pain, or other chronic pain . But overall baseline fi