geoffrey modest medical blogs

The USPSTF just came out with new recommendations to screen adults aged 18-79-yo for hepatitis C infection (see  hep c uspstf recs screen all jama2020  in dropbox, or  doi:10.1001/jama.2020.1123; or see   https://jamanetwork.com/journals/jama/fullarticle/2762185?resultClick=24  for the full systematic review leading to these new guidelines) Details: -- recommendation: screen adults aged 18-79 for hepatitis C virus (HCV) infection, grade B recommendation -- the recommendation:      --  all asy mpt omatic adults  in that age group without known liver disease have a one-time screen     -- those at high risk, in particular with past or current injection drug use (highest risk factor), should be screened periodically (though no clear evidence on what that screening interval should be) -- this is an expansion of the prior recommendation of screening all born between 1945 and 1965, as well as others at high risk (no...

hepatitis c screen all, and treatment changes G      Geoff A. Modest, M.D. Mon 10/7/2019 7:51 AM Geoff A. Modest, M.D.  The US Preventive Services Task Force issued a draft recommendation to screen all adults aged 18-79 for hepatitis C (see  https://www.uspreventiveservicestaskforce.org/Page/Document/draft-recommendation-statement/hepatitis-c-screening1  ), as a Grade B recommendation (high certainty that net benefit is moderate, or  moderate certainty that net benefit is moderate to substantial.) -- risk assessment:  all adults 18-79 should be screened , though consider screening if younger or older than that if risk factors     --there have been recent increases in hepatitis C virus (HCV) infection, mostly in young people who inject drugs (PWID); 1/3 of PWID aged 18-30 are infected with HCV and 70-90% of older PWID are infected...