geoffrey modest medical blogs

  A recent Consumer Reports presented their findings of high lead and cadmium levels in dark chocolate (see  https://urldefense.com/v3/__https://www.consumerreports.org/health/food-safety/lead-and-cadmium-in-dark-chocolate-a8480295550/__;!!CvMGjuU!-Vz2xulBoWBHTLIPaUmGkzksm8YNdbivSm1Qxs_d75rOsjAxI1ziRT5GJLPze_PBtvfz_gez7Wq6h6acCyhUmFc$  ) Details:  -- the following are the results of the Consumer Reports findings. for the analysis, they used the low-bar of California's maximum allowable dose level (MADL) for lead (0.5 mcg) and cadmium (4.1 mcg), and presented the findings as the percentages of MADL in an ounce of each of the chocolates (there are no federal limits for the amount of these metals that most foods can contain...): Safer choices: -- Mast organic dark chocolate: 80% Cocoa: lead 14%, 40% cadmium -- Taza Chocolate organic deliciously dark chocolate: 70% Cacoa: 33% lead, 74% cadmium --   Ghirardelli intense dark chocolate: 86%  Cacoa : 36% lead, 39% ...

  A recent large study found that a commercial multivitamin-mineral (MVM, Centrum Silver) tablets improved cognitive function (see   cognitive function inc with MVI AlzDem2022   in dropbox, or DOI: 10.1002/alz.12767 ). thanks to Karen Henley for bringing this to my attention   Details : -- the COSMOS-Mind study (Cocoa Supplement and Multivitamin Outcomes Study of the Mind,  COSMOS-m ), an ancillary study to a large pragmatic, placebo-controlled, 2x2 factorial clinical trial of cocoa extract (CE) and/or MVM on cardiovascular and cancer outcomes. patients were enrolled from 2016-17 [a pragmatic trial is more of a real-world trial, often done by phone interviews of patients, instead of a more structured efficacy trial]      -- CE contained 500mg of cocoa flavanols including 80 mg (-)-epicatechins, 50 mg theobromine, and 15 mg caffeine -- 2262 participants (mostly from the Brigham and Women's Hospital i...