geoffrey modest medical blogs

  A recent article confirmed a strong relationship between stress and cognitive decline in older US adults ( see  stress dec cognitive function JAMA2023 in dropbox, or  doi:10.1001/jamanetworkopen.2023.1860 )   Details : -- 24,448 participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS study), a national population-based cohort of Black and White participants at least 45 years old sampled from the US population, recruited between 2003-2007; all had ongoing annual follow-up and analysis from 2021-2022     -- the REGARDS group was selected from a commercial nationwide list from Genesys   (a commercial database of the US population)     -- REGARDS oversampled Black participants as well as those living in the southern US states where the stroke risk is highest (“stroke belt”) and the coastal plains of North Carolina, South Carolina, and Georgia, where there is a higher stroke mortality (the “strok...

  in the current enlightened approach to reassessing race-based normative values, the MESA Lung Study found that race/ethnicity-neutral spirometry values were appropriately predictive of long-term clinical chronic lower respiratory disease (see  spirometry no diff outcomes by race AmJRespCritCare2021  in dropbox, or  DOI: 10.1164/rccm.202107-1612OC ) Details: -- standardized spirometry done by the Multi-Ethnic Study of Atherosclerosis (MESA) Lung Study, a population-based, prospective cohort study of 3,344 White, Black, Hispanic, and Asian adults from 2004-2006 -- participants were from six US communities with a minimum of two racial/ethnic groups recruited at each site --  chronic lower respiratory disease ( CLRD)  was a physician-based diagnosis, and included the categories of COPD, chronic bronchitis, emphysema, and asthma -- baseline demographics:      -- mean age 65, self-reported race/ethnicity was 36% White/25% Black/23% Hispanic/...