response to WHO: Dolutegravir is best drug in pregnancy
ray martin emailed me back as below, raising the unfortunately common issue of PEP (post-exposure prophylaxis) for needlesticks and the recommendation to use raltegravir (and INSTI which may actually be more likely to have an effect on folate) as opposed to dolutegravir in "persons who are pregnant or are of childbearing potential", per UpToDate raises suggestion that women of childbearing potential might be advised to try to avoid pregnancy during the time taking PEP... and, if possibly very early pregnancy, checking pregnancy test and discussing pros/cons of INSTI-based regimen geoff From: Ray Martin Sent: Monday, August 12, 2019 8:29 AM To: Geoff A. Modest, M.D. < GModest@uphams.org > Subject: Re: WHO: Dolutegravir is best drug in pregnancy Hi Geoff, Thanks for this. Working in employee health I write Rx's for PEP following high-risk needle sticks and have been prescribing raltegravir for pregnant...