geoffrey modest medical blogs

  a recent article found that aspirin reduced the severity of metabolic dysfunction-associated steatotic liver disease (MASLD): NAFLD aspirin dec liver fat JAMA2024  in dropbox, or doi:10.1001/jama.2024.1215. The commentary section below details the new nomenclatures for steatotic liver diseases, per the AASLD (the American Association for the Study of Liver Diseases)   Details : -- 80 participants 18 to 70 years old who had established MASLD were enrolled in a six-month phase-2 randomized double-blind placebo-controlled clinical trial     -- patients were excluded if they had other causes of hepatic steatosis, including significant alcohol intake (at least three drinks per day for men or two drinks a day for women), diagnosis of viral hepatitis, hemochromatosis, alpha-1 anti-trypsin deficiency, Wilson’s disease, autoimmune hepatitis, or HIV -- patients were randomized to aspirin 81 mg versus matching placebo, along with standard nutritional couns...

Fw: generalists: 2 heads better than one, and better than specialists G      Geoff A. Modest, M.D. Mon 3/4/2019 7:06 AM Geoff A. Modest, M.D.  An interesting article just came out finding increased diagnostic accuracy of multiple physician involvement (collective intelligence) vs an individual physician, and generalist groups outperformed individual specialists in that field (see  primary care multiple MDs better jamaopen2019  in dropbox, or doi:10.1001/jamanetworkopen.2019.0096 ). Details: -- data were from the Human Diagnosis Project (Human Dx) platform, one used by physicians and medical students to practice authoring and diagnosing teaching cases. These cases are from their own clinical practice and identify the intended diagnosis or the differential diagnosis. Respondents generate a ranked differential diagnosis and are notified if they are  correct or n...