diverticulitis Rx: amoxacillin/clavulanate
A comparative effectiveness study sponsored by the NIH found that the combination amoxicillin/clavulanate was as effective as, and less onerous than, treatment with metronidazole/fluoroquinolone ( see diverticulitis augmentin AIM2021 in dropbox, or doi:10.7326/M20-6315 ) Details: -- nationwide population claims -based data in the US for those 18-64yo with private employer-based insurance through the MarketScan database (from 2000-2018) and a 20% sample of Medicare claims for those 65 and older (2006-2015), for immunocompetent patients with acute diverticulitis in the outpatient setting -- demographics, in brief: -- MarketScan: median age 52, major comorbidities: GERD 8%/arthritis 5%/obesity 4%, meds: antihypertensives 36%/statins 23%/NSAIDs 20%/PPIs 16%/SSRIs 12%, 96% without an inpatient admission in the past year. CT scans were done more commonly in the metronidazole/fluoroquinolone group (61% vs 49%) ...