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colchicine decreases cardiovasc events if diabetes and recent MI

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  A recent study found that patients with type II diabetes and a recent myocardial infarction had impressive decreases in a composite of cardiovascular events by being randomized to colchicine (see   colchicine helps if MI and DM DiabCare2024  in dropbox, or doi.org/10.2337/dc23-1825   Details : -- this current analysis was a prespecified analysis from the Colchicine Cardiovascular Outcomes Trial (COLCOT), a  Canadian with patients enrolled from December 2015 to July 2019     -- the original COLCOT study involved 4745 patients who had an MI in the prior 30 days and were randomized to colchicine 0.5 mg a day versus placebo, finding a 23% reduction of the cardiovascular composite outcomes (death from cardiovascular causes, resuscitated cardiac arrest, MI, stroke, or urgent hospitalization for angina leading to coronary revascularization) over a median follow-up of 22.6 months: see ( s ee cad colchicine postMI nejm2019  in dr...