H Pylori: resistance patterns in the US
A new article explored the rates of antimicrobial resistance in H. pylori isolates from patients across the US and Europe, finding profound levels of resistance especially to metronidazole and clarithromycin ( see H pylori antimicrobial resistance AmJGastro2022 in dropbox, or doi: 10.14309/ajg.0000000000002045) Details: -- H. pylori isolates were obtained from 907 patients in 103 centers across the US and 5 European countries -- mean age 51, 70% female, 90% white/8% Black -- BMI 29, current smoker 21%/ex-smoker 20%/never smoker 60%, alcohol use a couple of days per month 33%/couple of days per week 18%/every day 2%/never 45% -- dyspepsia 98%/nonbleeding peptic ulcer 2%/history of untreated peptic ulcer 2%/long term NSAIDs at a stable dose 3% -- H pylori infection was confirmed by 13 C-urea breath test and gastric biopsy specimens Results : -- clarithromycin resista...