statins dec dementia after concussion
As an addendum to the prior blog on atorvastatin improving renal function (see http://gmodestmedblogs.blogspot.com/2019/05/atorvastatin-retards-renal-function.html ), a recent study came out suggesting that statins decrease the risk of dementia following a concussion (see concussion statin dec dementia jamaneuro2019 in dropbox, or doi:10.1001/jamaneurol.2019.1148). Details: -- population-based study in Ontario Canada from 1993 to 2013, then continued until March 2016 for follow-up -- older adults diagnosed with a concussion, excluding severe cases resulting in hospitalization and those with a prior diagnosis of dementia or delirium -- they measured the long-term incidence of dementia, comparing those who had a statin prescription written within 90 days of the concussion vs not [this is a simple database linkage, so no information about why they were on a statin] -- 28,815 patients were diagnosed as having a concussion -- median age 76 (30% were >80 yo), 61% female, socio...