depression: add-on probiotics helps
Another article just came out suggesting a significant clinical role for the gut microbiota/brain interaction , this time for depression and anxiety . This small study found benefit in adding probiotics as adjunctive treatment for patients with insufficient response to antidepressant med s (see depression probiotics jamapsych2023 in dropbox, or doi:10.1001/jamapsychiatry.2023.1817 ) Details : -- 49 patients with moderate major depressive disorder (MDD) on antidepressants but having incomplete response to the meds were randomized to probiotics versus placebo in this UK study, between 2019-2022. -- Patients were 18 to 55 years old, were taking an approved antidepressant at a stable dose for at least six weeks, and did not have bipolar disorder, psychosis, eating disorders, personality disorders, substance dependence, suicidal ideation, serious medical illnesses, were taking gastrointestinal medications, ...