HPV-related cancers: oropharyngeal is most common
Background : -- chronic HPV infection is associated with six different anatomical regions: five are in the genital area (penis, cervix, anus, vagina, and vulva) and the sixth is in the oropharynx -- of note, there has been an increase in HPV-related cancers over time, with oropharyngeal cancer being the single most common HPV-related cancer in the US -- the CDC reported in 2019 ( https://www.cdc.gov/mmwr/volumes/68/wr/pdfs/mm6833a3-H.pdf ) that there were an average of 43,999 potential HPV-associated cancers (12.2/100K) annually, with 79% (34,800) attributable to HPV: -- oropharynx: 19,000 cases, 4.9/100K people, with 12,600 from the 9 serotypes covered by the vaccine, 900 from other HPV serotypes, and 5,500 that were HPV-negative -- cervix: 12,015 cases, 7.2/100K people, with 9,700 from the 9 serotypes covered by the vaccine, 1200 from other HPV serotypes, and 1,100 that were HPV-negative – the 9vHPV vaccine covers the following HPV types: 6,11,16,18,31,33,45,52,