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Showing posts with the label macrolides

community-acquired pneumonia: doxycycline works well

  It is generally problematic finding studies comparing newer antibiotics to older antibiotics (or   studies including  pretty much any other types of  older  medications), given that studies are largely paid for by drug companies, and it could turn out that the old medications are as good as , or perhaps better than,  the new ones the drug companies are trying to promote. An analysis, based on older studies, found that doxycycline seems to be as efficacious as macrolides or fluoroquinolones in treating mild - to - moderate community acquired pneumonia (see   pneumonia CAP doxycycline helps CID2023  in dropbox, or doi.org/10.1093/cid/ciac615)    Details :  -- a systematic review/meta-analysis of 6 randomized controlled trials with 834 patients performed between 1984 and 2004 that compared doxycycline to  3  macrolides (roxithromycin, spiramycin, and erythromycin) and  3  fluoroquinolones (ofloxacillin, fleroxacin...