HPV vax: decreased cervical cancer mortality in young women
a recent letter-to-the-editor documented a dramatic decrease in cervical cancer deaths in US women younger than 25 years old, over the time period of 1992-2021. This was likely attributable to the advent of the HPV vaccine (see dec cervical cancer mortality in young women JAMA2025 in dropbox, or doi:10.1001/jama.2024.22169) Details : -- cervical cancer mortality trends were obtained from the National Center for Health Statistics -- main outcome: the changes in cervical cancer mortality from 1992 to 2021, with specific reference to women <25yo Results : -- 398 cervical cancer deaths were reported from 1992-2021 in women <25yo -- between the 3-year cycle of 1992-94 to 2013-15, there was a largely linear gradual decline in the cervical cancer mortality, at a rate of 3.7%/year (-4.8% to -2.1%) -- the cervical cancer mortality rate then decreased from 2016-2021 at 15.2%/year (-21.9% to -7.8%), and with an overall 62% reduction (see grap...