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diabetes risk: BMI less good predictor

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  Another study just came out finding that BMI is an inferior predictor of the development of type II diabetes (see BMI less good predictor for diabetes DiabReseClinPract2024  in dropbox or https://doi.org/10.1016/j.diabres.2024.111888 )   Details : -- 155,623 Japanese participants who had medical checkups when working at the Panasonic Corporation between 2008 and 2021, having had two consecutive health examinations during that interval, were evaluated for how several different anthropometric indices of adiposity were associated with subsequent development of type II diabetes     -- 115,036 men and 40,587 women were evaluated -- the anthropometric indices assessed:       -- BMI     -- WC, waist circumference     -- wBMI, waist circumference times the BMI (the waist-corrected BMI)     -- ABSI , a-body shape index, the waist circumference divided by the BMI to the two thirds power times the square root of the height, a measure of the body shape (different from the body
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cytisine for smoking cessation

  The NY Times had a recent article on cytisine as an effective treatment for smoking cessation:  https://www.nytimes.com/2024/10/02/well/quit-smoking-cytisine.html?smid=nytcore-ios-share&referringSource=articleShare&sgrp=c-cb   they make a few well-substantiated points: -- it is pretty easy to stop smoking, the issue is maintaing abstinence (and 47%  of those who try to quit are smoking 1 year later:  https://pmc.ncbi.nlm.nih.gov/articles/PMC3723776/  ) -- cytisine was developed as a pill in Bulgaria in 1964 and has been used in Eastern Europe for 50 years for smoking cessation -- cytisine was approved in Canada in 2017 and Britain last year for smoking cessation -- there have been many scientific articles showing a great effect of cytisine in smoking cessation (several noted below), with a 2014 editorial by Nancy Rigotti referring to cytisine as “a tobacco treatment hiding in plain sight”:  https://www.nejm.org/doi/full/10.1056/NEJMe1412313     Commentary: --   cigarette smok
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MASLD aspirin may help decrease liver fat

  a recent article found that aspirin reduced the severity of metabolic dysfunction-associated steatotic liver disease (MASLD): NAFLD aspirin dec liver fat JAMA2024  in dropbox, or doi:10.1001/jama.2024.1215. The commentary section below details the new nomenclatures for steatotic liver diseases, per the AASLD (the American Association for the Study of Liver Diseases)   Details : -- 80 participants 18 to 70 years old who had established MASLD were enrolled in a six-month phase-2 randomized double-blind placebo-controlled clinical trial     -- patients were excluded if they had other causes of hepatic steatosis, including significant alcohol intake (at least three drinks per day for men or two drinks a day for women), diagnosis of viral hepatitis, hemochromatosis, alpha-1 anti-trypsin deficiency, Wilson’s disease, autoimmune hepatitis, or HIV -- patients were randomized to aspirin 81 mg versus matching placebo, along with standard nutritional counseling for MASLD; medication a
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