geoffrey modest medical blogs

  A recent study reaffirmed a relationship between H Pylori infection in the development of Type II diabetes (see  H pylori and development of diabetes BMCendo2024  in dropbox, or  https://doi.org/10.1186/s12902-024-01694-2 )   Details : -- 4406 participants attending their annual health checkups at a single Chinese hospital were included in this study to assess the correlation between the incidence of Type II diabetes and H. pylori infection.     -- 2053 participants were H. pylori positive as detected by breath test, 2353 were H. pylori negative -- Mean age 48, 37% female -- BMI 24, fasting blood glucose 95 mg/dL, total cholesterol 174/HDL 52/LDL 108 mg/dL -- exclusion criteria included patients with severe hepatic, renal, cardiovascular or cerebrovascular diseases; those with malignant tumors or autoimmune diseases; and those with other endocrine disorders   -- main outcomes: assess the correlation between the incidence of Type II diabetes...

  A recent study found that in patients with gastric cancer who had had a radical gastrectomy and were H pylori positive  but then were treated  for the infection   had significantly improved survival   vs  those not treated  (see   h pylori rx in survival gastric ca JAMA2024  in dropbox, or doi:10.1001/jamanetworkopen.2024.3812)   Details : -- 1293 patients were found who had had a radical gastrectomy and were H. pylori positive in a retrospective cohort study in a single referral hospital in China from 2010 to 2019     -- patients had gastric or esophagogastric junction adenocarcinoma and underwent curative gastrectomy with D2 lymphadenectomy      -- patients were divided into two groups: 125 (10%) of the 1293 patients had H. pylori therapy during the perioperative period, and 1168 patients did not -- median age 59, 67% male, BMI 22, smokers  35% , hypertension 13%, coronary heart disease 5%, dia...