latent TB: when should we treat it?
I bumped into an article from 2018 which challenged the current approach of testing/treating latent tuberculosis (see TB LTBI if treat BMJ2018 in dropbox, or doi: 10.1136/bmj.k2738). This article is replete with references on the many cited studies, though some of them are very old and not accessible for my review. the article is open access and should be downloadable easily Details: -- natural history of TB infection, from the pre-antibiotic era: -- there were 3 longitudinal studies of TB acquisition and progression -- a 1950 article by Poulsen in the Acta Tuberc Scand Journal on the incubation period of tuberculosis, when he was working at the Faroe Islands from 1939 to 1947 (isoniazid, or INH, became available in 1952), at which time he could pinpoint the time of exposure to TB within a two week period, and of...