LDL goal after new-generation stents
A secondary analysis of the CONNECT trial, that stands for (a bit of a stretch...) “A Randomized Comparison of Long-Term Vascular Healing Between Biodegradable Polymer vs Durable Polymer Everolimus Eluting Stents in Acute ST-Elevation Myocardial Infarction” found that a lower target LDL level was associated with decreased neoatherosclerosis, which is associated with subsequent stent failure (see LDL goal after stent JAMAcardiol2025 in dropbox, or doi:10.1001/jamacardio.2025.4723) Details : -- the CONNECT trial was a prospective, multicenter, open-label, assessor-blind, randomized clinical trial to investigate the association between achieving guideline-endorsed target LDL levels with long-term neoatherosclerosis formation after current-generation drug-eluting stent implantation. This trial was conducted in 7 centers in 2 countries (Switzerland and Japan) -- patients at least 18 years old were eligible if they presented with a...