fracture surgery: weak opiates after discharge as good as oxycodone
Patients sent home after surgical management of orthopedic fractures do as well with acetaminophen with codeine as with oxycodone (see opiates after fracture mild as good jama2021 in dropbox or doi:10.1001/jamanetworkopen.2021.34988) Details : -- 120 patients in Australia with one or more acute orthopedic fractures requiring surgical fixation were randomized into the oxycodone group versus acetaminophen plus codeine, from July 2016 to August 2017 -- mean age 37, 45% men, BMI 28, at least one comorbidity 22%, recreational drug user 2%, weekly alcohol consumption 39%, premorbid pain medication use 7%, non-smoker 70% -- one fracture in 87%/more than one 13%; mechanism of injury road-related 29%, fall 35%, blunt or crush trauma 34%; upper extremity fracture 29%, lower extremity 56%, pelvis 3%, multiple regions 12% -- all patients had sustained a non-pathological fracture of a long bone, or the pelvis, patella, calcaneus, or ta...