coronary artery calcium dec plaque progression?
the CAUGHT-CAD trial was done to see if adding coronary artery calcium (CAC) scoring to our calculated cardiovascular risk would lead to a decrease in the progression of atherosclerotic plaques (see coronary calcium and statin dec plaque progression JAMA2025 in dropbox, or doi.org/10.1001/jama.2025.0584 ). Overall, this was not a decisive trial, but it provided a segue to me to discuss the relative merits and weaknesses of CAC scores and benefits of coronary CT angiography (CCTA) Details: -- in this prospective, randomized, open-blinded endpoint clinical trial in seven hospitals across Australia, 365 participants 40 to 70 years old who were asymptomatic and had a first-degree relative with coronary artery disease (CAD) younger than 60 years old or a second degree relative with CAD onset at younger than 50 years old, from 2013-2020. -- these participants all had intermediate cardiovascular risk and were not to be on statins, per the Au...