vitamin D assoc with less telomere shortening
A recent study found that vitamin D supplementation was associated with less telomere shortening, which could foretell deceasing aging effects and associated severe diseases, in a pre-publication paper (see vit d longer telomeres AmJClinNut2025 in dropbox, or DOI: 10.1016/j.ajcnut.2025.05.003 ) Details : -- this current study was part of the VITAL study (Vitamin D and Omega-3 trial), a large, randomized, double-blind, placebo-controlled trial with a 2x2 factorial design of vitamin D 3 2000IU/d (equivalent to 50mcg) and/or marine n-3 fatty acids (n-3 FAs) 1 gm/d for 5 years. randomization was from 2011 to 2014, with intervention until the end of 2017 -- the overall study included 25,871 US females aged at least 55yo and males aged at least 50yo -- the VITAL Telomere study, which included 1054 participants, was designed to assess the effect of these supplements on leukocyte telomere length (LTL) -- LTL was assess...